DIPSS
DIPSS prognostic score              
               
The Dynamic International Prognostic Scoring System (DIPSS)
can be applied at any time in disease course.     1. Sum the points for each prognostic factor    
Value Points
Prognostic variable 0 points 1 point 2 points
Age (years)*
Age (y) ≤ 65 > 65 -
WBC count (x 109/L)*
White blood cell count (x109/L) ≤ 25 > 25 -
Hemoglobin (x g/dL)*
Hemoglobin (g/dL) ≥ 10 - < 10
Peripheral blood blasts (% of leukocytes)*
Peripheral blood blasts (%) < 1 ≥ 1 -
Constitutional symptoms
Constitutional symptoms? No Yes -
        2. Determine DIPSS risk category and prognosis    
DIPSS score DIPSS risk category Median OS (y)
DIPSS score   0 Low Not reached
DIPSS risk group   1-2 Intermediate-1 14:02
3-4 Intermediate-2 4
5-6 High 01:05
Reference              
Passamonti F, Cervantes F, Vannucchi AM, Morra E, Rumi E, Pereira A et al. A dynamic prognostic model to predict survival in primary myelofibrosis: a study by the IWG-MRT (International Working Group for Myeloproliferative Neoplasms Research and Treatment