International Prognostic Index (IPI) Prognostic scoring system for aggressive non-Hodgkin lymphoma 1. Sum the number of risk factors Value Points Risk factors Age (years) Age > 60 years LDH Raised (Yes-No) -Please Select NO YES Raised LDH: YES=1 NO=0 Performance status Performance status ≥ 2 Ann Arbor stage Ann Arbor stage ≥ 3 extranodal sites of disease (number) Two or more extranodal sites of disease 2. Determine risk category and prognosis Risk factors (n) Risk category DLBCL 3yr OS2 PTCL 5yr OS3 0 - 1 Low 91% 50% Sum of score 2 Low-intermediate 81% 33% Risk category 3 High-intermediate 65% 16% 4 - 5 High 59% 11% References A predictive model for aggressive non-Hodgkin’s lymphoma. The International Non-Hodgkin’s Lymphoma Prognostic Factors Project. New Engl J Med 1993; 329: 987-994.