IPSET
Essential thrombocythemia       International Prognostic Score for Thrombosis in Essential Thrombocythemia (ET)
         
IPSET-thrombosis    
  Value Points     1. Calculate IPSET-thrombosis score
Age (years)*
Patient age?  under 60 years  60 years or older
Prior thrombosis
Prior thrombotic event?  No  Yes
Cardiovascular risk factors*
Cardiovascular risk factors present?  No  Yes
JAK2V617F mutation
JAK2 V617F mutation detected?  No  Yes
*One or more of: hypertension, diabetes mellitus, active smoking
One or more of: hypertension, diabetes mellitus, active smoking
          IPSET-thrombosis score:
IPSET-thrombosis score     2. Determine risk group and prognosis
IPSET-thrombosis risk group     Score Risk category Annual thrombosis risk
0 - 1 Low 1.03%
2 Intermediate 2.35%
3 - 6 High 3.56%
               
Reference              
Barbui T, Finazzi G, Carobbio A, Thiele J, Passamonti F, Rumi E et al. Development and validation of an International Prognostic Score of thrombosis in World Health Organization-essential thrombocythemia (IPSET-thrombosis). Blood 2012; 12: 5128-33.