Mantle cell lymphoma International Prognostic Index (MIPI) Calculator Prognostic index for advanced-stage mantle cell lymphoma Value Points Age (years) The MIPI is applied at the time of diagnosis. If lymph node Ki67 proliferation index is available, use the MIPIb combined biologic index instead. LDH (U/L) Upper limit of normal for serum LDH (U/L) The MIPI is calculated using the following formula: [0.03535 × age (years)] + 0.6978 (if ECOG > 1) + [1.367 × log10(LDH/ULN)] + [0.9393 × log10(white cells per uL blood)]. white blood cell count (x 109/L) ECOG Performance status Sum of score A score < 5.7 indicates low-risk disease, 5.7 - 6.2 indicates intermediate risk, and >= 6.2 high risk. Risk category References Hoster E, Dreyling M, Klapper W, Gisselbrecht C, van Hoof A, Kluin-Nelemans HC et al. A new prognostic index (MIPI) for patients with advanced-stage mantle cell lymphoma. Blood 2008; 111: 558-565.