MDS
WHO classification-based prognostic scoring system for myelodysplasis    
        1. Sum the scores for each factor (WHO category, karyotype, transfusion requirement
  Value Points   Score WHO Category Karyo­type (1) Trans­fusion require­ment (2)
WHO category
0
Karyotype
1 Regular
Transfusion requirement
2 Poor -
3 RAEB-2 - -
SUM of SCORE     2. Use summed scores to determine risk category and prognosis
RISK CATEGORY     Score Risk category Median OS (months) 2 year proba­bility of progres­sion to AML
0 Very low 141 3%
1 Low 66 6%
2 Intermediate 48 21%
3 - 4 High 26 38%
5 - 6 Very high 9 80%
Reference
Malcovati L, Germing U, Kuendgen A, Della Porta MG, Pascutto C, Invernizzi R et al. Time-dependent prognostic scoring system for predicting survival and leukemic evolution in myelodysplastic syndromes. J Clin Oncol 2007;25:3503-3510