Follicular Lymphoma International Prognostic Index 2 (FLIPI2) Calculator    
Prognostic score for untreated follicular lymphoma  
Applies at the time of first treatment.
  Value Points     1. Sum the number of risk factors to calculate FLIPI-2 score  
Age (years)
Age:  < 60 years  60 years or older
Serum beta 2 microglobulin
Serum beta 2 microglobulin:  Normal  Raised
Bone marrow involvement
Bone marrow involvement:  Absent  Present
Longest diameter of largest involved node (cm)
Longest diameter of largest involved node:  Less than 6 cm  6 cm or more
Hemoglobin (g/dL)
Hemoglobin:  12 g/dL or greater  < 12 g/dL
          2. Determine risk category and prognosis    
          FLIPI-2 score FLIPI-2 risk category 5 year PFS (%)1 5 year PFS (%)2
Sum of score     0 Low risk 80 76
Risk category     1 - 2 Intermediate risk 51 49
3 - 5 High risk 19 37
Federico M, Bellei M, Marcheselli L, Luminari S, Lopez-Guillermo A, Vitolo U et al. Follicular lymphoma international prognostic index 2: a new prognostic index for follicular lymphoma developed by the international follicular lymphoma prognostic factor p